GWAS Annotated: FBXL4

Gene: F-box and leucine rich repeat protein 4

GeneGHIDGWAS HitLead SNP-log10PTypeScoreEliteAssociation EvidenceLocationExternal LinksTFBSs
FBXL4GH06J098022-6:98022767:G:A0.0132Enhancer63-eQTLschr6:98022519-98022827--
FBXL4GH06J098036-6:98036577:T:C0.0183Enhancer153EliteeQTLschr6:98036404-98036714ENSR6_93FWM3
CHD7SIN3AHDAC2NANOGSMARCA4USF1SMC3
FBXL4GH06J098039-6:98041778:C:T6.7089Enhancer315EliteeQTLschr6:98039390-98042574ENSR6_BPGC3, ENSR6_84TSDB
RBBP5SMARCA4MAFKASH2LMAFFTRIM28CHD7JUNDHDAC2JUNNANOGSP1EP300YY1BCL11ACTCFRAD21SMC3SMARCA4EGR1HDAC2MAFKMAFFZNF316TRIM28GATA3PAX5MXI1RCOR1GATA2SMARCA4
FBXL4GH06J098042-6:98043334:G:A5.6965Enhancer1-eQTLschr6:98042869-98043481--
FBXL4GH06J098043-6:98045334:T:G5.5961Enhancer256EliteeQTLschr6:98043952-98045362-
MXI1EP300SMC3RAD21SMARCA4SMARCA4
FBXL4GH06J098056-6:98057885:T:C4.3176Enhancer63-eQTLschr6:98056157-98058182--
FBXL4GH06J098832-6:98832543:G:A0.8783Enhancer240EliteeQTLschr6:98832440-98832999ENSR6_BPLKM, ENSR6_5T8MKS, ENSR6_93G86F, ENSR6_77RWN3
EZH2SUZ12KDM4ARNF2L3MBTL2ZBTB33HNRNPKPOLR2ACTCFMXI1EP300BHLHE40FOSAGO1TRIM28CTCFRAD21
FBXL4GH06J098834-6:98833860:T:C0.8613Enhancer202EliteeQTLschr6:98833744-98833894-
EZH2SUZ12RNF2MXI1TRIM28L3MBTL2ZBTB33HNRNPLLHDAC1ZFXXRCC5KDM4ASIN3AHDAC2RCOR1NCOA1HDAC2SMARCE1ZNF282
FBXL4GH06J098833-6:98834265:T:A0.8606Promoter/Enhancer461EliteeQTLschr6:98833924-98835201ENSR6_93G86W, ENSR6_5T8MW7, ENSR6_5T8MZ6, ENSR6_93G876
EZH2SUZ12RNF2TRIM28HNRNPLLKDM4ASIN3ANCOA1HDAC2SMARCE1ZNF282ATF7DPF2SMARCA4FOXM1ZNF263HDAC1MNTSP1STAT1TRIM24PRDM10CEBPBKDM1AIRF2IRF1SIN3AIKZF1TCF12ARID1BCBFA2T3ZBTB7ASOX6NEUROD1TEAD4DACH1MTA2STAT2EP300STAT5ATBL1XR1MEIS2E2F1TAL1GABPARB1RESTPKNOX1CBFA2T2NCOR1GATA2RFX5NFXL1MBD2EGR1RBBP5ZNF143NRF1RFX1GMEB1MXI1MAXTRIM24EGR1TBPUSF1BHLHE40CREME2F6ZNF639ASH2LL3MBTL2ZNF217ZNF444MLLT1ZNF830MGATAF1CTBP1SMARCA4HES1POLR2ASUZ12RAD21POLR2GNCOA6ZNF184ZNF316ZFP91HDAC1HDAC2NFICEZH2SMC3ZNF687YY1RUNX3CHD1E2F6EGR1SUZ12EZH2
FBXL4GH06J098839-6:98839259:C:G0.8199Enhancer105-eQTLschr6:98839190-98841070ENSR6_93G88J
SUZ12CTCFSMC3TRIM28RAD21EZH2MXI1CUX1TRIM22YY1SMARCA4RESTEZH2GATA3
FBXL4GH06J098845-None0.0000Enhancer357EliteTF_co-expression,Distancechr6:98845664-98845954ENSR6_CCRS9
EZH2RBBP5RBM39MXI1KDM4ACTCFZNF263SMC3ZNF217POLR2APHF20L3MBTL2RAD21ZEB1IKZF1TAF1CC2D1ANFATC3ZNF24PCBP2RCOR1RB1ZNF444MCM2NCOA1YY1SMARCA4ARID2MCM5NR3C1ZNF143RESTBHLHE40MAFKTRIM22
FBXL4GH06J098847-6:98847314:T:C0.9000Enhancer56-eQTLs,Distancechr6:98847140-98848807ENSR6_CCRSG
SUZ12CTCFSMARCA4EZH2CTCFEP300AGO2YY1ETS1EZH2
FBXL4GH06J098932-None0.0000Enhancer1-Distancechr6:98932400-98933000-
SMARCA4
FBXL4GH06J098944-6:98944876:T:C0.6109Enhancer252EliteDistancechr6:98944672-98945136ENSR6_93G9CW
ASH2LHDAC2KDM1AKDM5ATCF7L2CHD4CREMGATA3ZBTB33CTCFNR2F6RXRARAD21FOXA1FOXA2GATA4JUNDSP1TAF1SKIFOXP1HNF4AEP300TCF7ZNF263TRIM28CBFA2T3ARID3AYY1POLR2AFOXA1NFICFOXA2
FBXL4GH06J098945-6:98946102:A:C0.6895Promoter/Enhancer544EliteeQTLs,Distancechr6:98945729-98948600ENSR6_CCS4M, ENSR6_BPM7F, FBXL4_1
ZBTB40HNF4ASP1ARID3ARXRATBPMLLT1ZSCAN29CHAMP1DPF2SMARCE1SMARCA4GATA2EHMT2NFRKBNBNYY1GATAD2BNFICCBFBHDAC1ASH2LCTCFPOLR2APMLTBPRUNX3ATF7PHF8IKZF1RUNX3ZNF592MNTRBFOX2MAXCREB3L1RNF2MYCAGO2SIN3ARESTEP400NRF1RBM39GMEB1POLR2GMGASMARCA4MXI1EP300SMC3HES1TAF1CREB1RAD21L3MBTL2ZNF316EGR1ZBTB7AYY1FOXK2PAX5FOXA2BHLHE40E2F6FOXA1ZFXKDM5BDPF2CREMPRPF4SAP30HNRNPLPHF20FUSIRF1CTBP1ZNF687RESTUBTFLEF1ELF1NFICGABPB1GABPARB1RUNX3KDM4AHCFC1HNRNPLLTAF7MYCSMAD5E2F6SP1MTA3MEF2BTAF9BRAD21CBX3ZNF592RXRAEBF1GMEB1IKZF1IRF1ZNF143TRIM28ARNTZSCAN29RFX5EP300ZBTB33
FBXL4GH06J098957-None0.0000Enhancer91-Distancechr6:98957564-98957714ENSR6_93G9HK
POLR2AJUNDNR2F1NR2F2GATA3CBFA2T3FOSGATA2
FBXL4GH06J098976-6:98978744:A:G0.5648Enhancer215EliteeQTLs,Distancechr6:98976847-98978971-
GABPAZFP91EP300ESR1NFE2L2IRF1
FBXL4GH06J099012-6:99013751:C:T0.7578Enhancer126-eQTLs,Distancechr6:99012704-99014273ENSR6_BPMJS
TAF9BFOSL2C11orf30JUNDFOSRFX1RCOR1MAFKFOSL1IKZF1DACH1ATF3ZNF316PKNOX1MAFFSTAT3NFE2L2CEBPBGATA2GATA3CEBPB
FBXL4GH06J099016-6:99016533:G:A0.5673Enhancer56-Distancechr6:99016444-99016594ENSR6_93GB5L
RESTRUNX3SPI1STAT3FOS
FBXL4GH06J099393-6:99394180:C:A0.7578Promoter/Enhancer568EliteTF_co-expressionchr6:99393173-99394774ENSR6_93GG6Z, COQ3_1
SKILNR0B1PAX8CHD1HDAC2NRF1ZNF24SMC3GATAD2BYY1HNF4APHF8MYCZNF384MAXKDM5BRXRAIRF4POLR2GMXI1RBFOX2POLR2AAGO1ZNF687CTCFSIN3AZFXIKZF1EZH2SKIBHLHE40RAD21KLF5RB1HDAC1HNRNPLLTAF1ZNF207EEDNR2F2ZBTB33ETS1TAF7RESTESRRATAF15ELF4TBPMNTFOXA1ATF3ZBTB7AE2F1ZNF639EGR1L3MBTL2EP300TRIM28RBBP5KDM5ABRCA1SP1ZNF143RBM39CREB3L1GABPB1NFICATF7EHMT2AGO2ASH2LFOXK2KDM1AKDM4BZBTB2MEIS2ZBTB40GATA3ELF1NFATC1PMLNCOA1GMEB1ZBED1MBD2NFRKBATF2E4F1BCL3ZBTB11ZNF444E2F6E2F8AFF1NFATC3CREMNR2C1ELK1NR2F6C11orf30TRIM22CC2D1APOU2F2SIX5SMAD1ZFP91RLFNBNGABPAEP400CTBP1TRIM24CBX3CHAMP1IRF1HDAC3XRCC5CBX1ETV6ARNTSIN3BFOSL2ZHX1MYNNSOX6HCFC1ZNF217TCF12RELBNFE2BHLHE40THAP1ZZZ3ZNF384STAT2SMAD5TAF9BMTA3ETV4USF2ZEB2JUNDSTAT5APHF20USF1SRFZNF282MLLT1RUNX3BCORZMYM3
FBXL4GH06J099566-6:99568791:C:T1.9423Promoter/Enhancer598EliteTF_co-expressionchr6:99566759-99569400ENSR6_BPQJ5, ENSR6_BPQJ8, CCNC_1
CHD1POLR2AZEB2SMARCA4ZFXSMARCE1IKZF1ZNF316SMARCA5RBFOX2SIN3AJUNDFOSFOSL2BACH1STAT3GABPB1CREMGABPAASH2LU2AF1MAFKZSCAN29TAF1PCBP1EP300TCF12EZH2KDM5APHF8POLR2GCLOCKBRD4TRIM28MXI1RAD21MLLT1AGO1BCL3LCORLRBBP5RNF2DPF2EP400GATAD2BPTBP1ZNF639TRIM22FIP1L1IKZF2HDAC6HNRNPLLZBTB40CTCFSTAT5ANCOR1MBD2RBM22ATF3BACH1ZZZ3ARID3AHDAC3EGR1MTA3SMAD5EHMT2GATA1BCORZNF263NFICMNTTAF15ZBTB11CHD1RESTZBED1ZNF687ATF7ETS1RELBMEF2BYY1CTBP1RB1TCF7L2AFF1NRF1GATA4ZBTB2KDM5BHNRNPLZNF579E2F1MYCZNF444RBM39ETV4CREMARNTEEDHDAC1TAF7SKITBPESRRAMGAELF4AGO2ZNF207NBNDEAF1MAXZFP91ZBTB33GABPACC2D1ACBX5SIN3BWRNIP1ZNF830MTA2SMARCE1SP1MAFKSMC3TFAP4E2F6KLF5ELF1E2F8CBX1SMARCA5ZHX2XRCC5UBTFRLFTAF9BPHF20ZNF24E4F1SOX6HNF4ARXRASMAD1TBL1XR1MYNNPMLIRF1RCOR1STAT3HDAC2CREB1STAT1RUNX3FOXA1MEF2CTCF7SRFIRF2MYBL2SKILFOSL2ZKSCAN1ZNF217NEUROD1RFX5POU2F2NR2F6NCOA1L3MBTL2SPI1TRIM24TBX3TEAD4ZNF143SMARCA4NFE2L2C11orf30HCFC1TCF12NR2F2FOXM1GATA3NFATC3IRF4MEF2AZNF384PKNOX1MYBNR3C1USF1PHF21AJUNPAX5SIX5NFRKBNANOGPRDM10GMEB1IRF3ZNF282ZBTB7ANR2F1CHAMP1TBX21KDM4AKDM1AMLLT1ZNF184NR2C1CBX3ZHX1NFE2ATF2IRF5ARHGAP35NFIBMITFMAFFBRCA1CBFBCREB3L1BHLHE40HMBOX1RBM25ZNF384